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Excessive doses in children have led to respiratory depression, coma and death.
Symptomatic measures, such as increasing fluids, making sure children get enough rest and reducing the spread of the virus (including regular hand washing) should be practiced.
Side effects include: It is best not to drink alcohol when taking antihistamines, because this combination could result in excessive and potentially dangerous drowsiness.
Care needs to be taken with antihistamines when driving, flying or underwater diving.
An injection can be given in case of severe allergic reaction (although in such cases, adrenaline (epinephrine) may be more appropriate and can be life-saving).
Topical preparations (ointments and creams) are often applied to insect bites but are not very effective as the antihistamine chemical does not penetrate the skin well.
There are at least two kinds of histamine receptors, hence are mainly H1 blockers.
As well as tablets, antihistamines are available as injections, elixirs, and creams.
They do not always completely control the allergic reaction because they do not counteract other chemicals that may be responsible for the symptoms.
Fortunately, the child eventually recovered without any on-going ill-effects.
Sedating antihistamines have the ability to cross the blood-brain barrier, the ability to bind to non-histamine receptors and have less selectivity for peripheral or central H1-receptors.
Allergic symptoms occur when your body wrongly recognises a food or something (such as pollen spores) in your environment as a threat, and sends repair chemicals to deal to these perceived intruders.
One of these repair chemicals, histamine, is released from repair cells called mast cells, which are scattered throughout the body.
Because they are broken down by the liver, those with liver disease are best to take a reduced dose as there will be excessive levels circulating in the blood stream.